{"id":468112,"date":"2025-11-11T15:50:00","date_gmt":"2025-11-11T07:50:00","guid":{"rendered":"https:\/\/www.um.edu.mo\/news-and-press-releases\/press-release\/detail\/62532-2\/"},"modified":"2025-11-11T16:04:34","modified_gmt":"2025-11-11T08:04:34","slug":"62532","status":"publish","type":"post","link":"https:\/\/www.um.edu.mo\/pt-pt\/news-and-press-releases\/press-release\/detail\/62532\/","title":{"rendered":"UM undergraduate team wins gold medal at iGEM"},"content":{"rendered":"\n                        \n                        <p>A team of undergraduate students from the Faculty of\nHealth Sciences (FHS) at the University of Macau (UM) has won a gold medal at\nthe 2025 International Genetically Engineered Machine (iGEM) Competition held\nin Paris. Their award-winning project focuses on an innovative synthetic biology solution for termite\ncontrol. This is the seventh consecutive year that UM has won an award at iGEM,\nbringing the total number of gold medals to four.<\/p>\n\n<p>This year\u2019s competition attracted over 400 teams from\nmore than 50 countries and regions, including teams from renowned institutions\nsuch as the Massachusetts Institute of Technology (MIT), Harvard University,\nand Tsinghua University. The UM team comprised 13 undergraduate students in FHS\nand was guided by FHS Professor Garry Wong, Associate Professors Leo Lee Tsz On\nand Liu Tzu-Ming, as well as Assistant Professors Chen Qihan and Lei Chon Lok. In\nresponse to the growing issue of termite infestation, the team proposed an\ninnovative control solution that is highly effective, eco-friendly, and\nsustainable.<\/p>\n\n<p>Termites feed on cellulose and pose a threat to wooden\nstructures, and the issue of termite infestation is exacerbated by global\nwarming. Although existing termite control methods are effective, they are\nlimited by issues such as environmental pollution and high costs. The UM team used\nsynthetic biology techniques to engineer <i>E.\ncoli<\/i> to produce natural toxins and attractants. They then combined these with\nenhancers to formulate a highly effective, eco-friendly termite pesticide. The\nnatural toxins include EcTI, a plant-derived trypsin inhibitor that disrupts\ntermite digestion, and melittin, a peptide found in bee venom that damages the termite\u2019s\ngut microbes. Meanwhile, the attractant hydroquinone stimulates termite feeding\nbehaviour to increase bait intake. The team also developed two application\nmodels: an underground solid bait station for long-term colony eradication, and\na liquid injector for immediate treatment. Mathematical models were used to\noptimise bait placement strategies and simulate toxin transmission within\ntermite colonies, thereby enhancing control efficiency.<\/p>\n\n<p>The UM team members dedicated their spare time to\nproject design and experimentation, as well as conducting field visits in\nvarious places to gain a deeper understanding of termite ecology and the\napplication of control measures. By exchanging ideas with industry\npractitioners and scholars, the team refined their experimental design and gained\npractical insights into field trapping techniques, thereby enhancing the\nproject\u2019s feasibility and potential applications. With guidance from experts, the\nteam clarified the innovative aspects of their solution, making it more scientifically\nrigorous. Team leader Wang Ying, a third-year student in FHS, said that although\nthe process was filled with many unprecedented challenges, the rewards were\nplentiful. They had not only enhanced their professional knowledge but also developed\nsoft skills such as communication and teamwork.<\/p>\n\n<p>Founded by MIT in 2003, iGEM encourages participants to\nuse synthetic biology to address real-world problems. It has since become one\nof the world\u2019s most prestigious student competitions in biotechnology.<\/p>\n\n<table style=\"width: 44.7597%;height: 201px\"> <tbody> <tr style=\"height: 21px\"> <td style=\"height: 21px;width: 100.095%\" colspan=\"2\">Source: Faculty of Health Sciences<\/td> <\/tr> <tr style=\"height: 21px\"> <td style=\"height: 21px;width: 56.3278%;min-width: 120px\"> <\/td> <td style=\"height: 21px;width: 43.7669%\"> <\/td> <\/tr> <tr style=\"height: 21px\"> <td style=\"height: 21px;width: 100.095%\" colspan=\"2\">Media Contact Information:<\/td> <\/tr> <tr style=\"height: 21px\"> <td style=\"height: 12px;width: 100.095%\" colspan=\"2\">Communications Office, University of Macau<\/td> <\/tr> <tr style=\"height: 21px\"> <td style=\"height: 21px;width: 56.3278%;min-width: 120px\"> <\/td> <td style=\"height: 21px;width: 43.7669%\"> <\/td> <\/tr> <tr style=\"height: 21px\"> <td style=\"height: 21px;width: 56.3278%;min-width: 120px\">Albee Lei<\/td> <td style=\"height: 21px;width: 43.7669%\">Tel: (853) 8822 8004<\/td> <\/tr> <tr style=\"height: 21px\"> <td style=\"height: 21px;width: 56.3278%;min-width: 120px\">Bell Leong<\/td> <td style=\"height: 21px;width: 43.7669%\">Tel: (853) 8822 8009<\/td> <\/tr> <tr style=\"height: 21px\"> <td style=\"height: 21px;width: 56.3278%;min-width: 120px\">Email:<\/td> <td style=\"height: 21px;width: 43.7669%\"><a href=\"mailto:prs.media@um.edu.mo\">prs.media@um.edu.mo<\/a><\/td>\n<\/tr>\n<tr style=\"height: 21px\">\n<td style=\"height: 21px;width: 56.3278%;min-width: 120px\"> <\/td> <td style=\"height: 21px;width: 43.7669%\"> <\/td> <\/tr> <tr style=\"height: 21px\"> <td style=\"height: 21px;width: 56.3278%;min-width: 120px\"><\/td><td style=\"height: 21px;width: 43.7669%\"><\/td><\/tr>\n<\/tbody>\n<\/table>\n                        \n                        ","protected":false},"excerpt":{"rendered":"<p>A team of undergraduate students from the Faculty of Health Sciences (FHS) at the University of Macau (UM) has won a gold medal at the 2025 International Genetically Engineered Machine&#8230;<\/p>\n","protected":false},"author":1,"featured_media":468142,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[60],"tags":[],"class_list":["post-468112","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-press-release"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.5 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>UM undergraduate team wins gold medal at iGEM | Universidade de Macau<\/title>\n<meta name=\"description\" content=\"Universidade de Macau: Uma universidade abrangente p\u00fablica de n\u00edvel internacional fundada em 1981\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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